Skin contact with Cr-VI can cause inflammation, eczema, open sores and permanent sensitization that causes a skin condition called allergic contact dermatitis (ACD). Eczema and ACD have been found in populations exposed to environmental chromium contamination.
Ingestion of large amounts of Cr-VI can cause nausea, vomiting, stomach and intestine damage, anemia, kidney and liver damage. Cr-VI ingestion has been linked to a number of cancers2 and is starting to be considered a likely human carcinogen. Many of these affects have been observed in populations exposed to chromium contaminated drinking water.
Breathing in Cr-III and Cr-VI can irritate the nose, throat and lungs and produce inflammation. Cr-VI inhalation during chromium industrial work is known to cause nosebleeds, ulcers and holes in the septum (structure between your nostrils), asthma, lung cancer, sinonasal cancer and possibly other cancers. Breathing Cr-VI seems to be the most dangerous route of exposure. General population exposure to chromium contaminated soils has been linked to lung cancer.
Very few studies exist regarding potential reproductive and development effects on humans. Links between chromium exposure in the workplace and decreased sperm production and health have been documented. Informal observations have noted a high number of birth defects and pregnancy complications in people exposed to chromium